Cargando…
Cancer associated fibroblast derived SLIT2 drives gastric cancer cell metastasis by activating NEK9
The secretory properties of cancer-associated fibroblasts (CAFs) play predominant roles in shaping a pro-metastatic tumor microenvironment. The present study demonstrated that SLIT2, an axon guidance protein, produced by CAFs and promoted gastric cancer (GC) metastasis in two gastric cancer cell lin...
Autores principales: | Lu, Guofang, Du, Rui, Dong, Jiaqiang, Sun, Yi, Zhou, Fenli, Feng, Fan, Feng, Bin, Han, Ying, Shang, Yulong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344862/ https://www.ncbi.nlm.nih.gov/pubmed/37443302 http://dx.doi.org/10.1038/s41419-023-05965-z |
Ejemplares similares
-
NEK9, a novel effector of IL-6/STAT3, regulates metastasis of gastric cancer by targeting ARHGEF2 phosphorylation
por: Lu, Guofang, et al.
Publicado: (2021) -
Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition
por: Sun, Yi, et al.
Publicado: (2022) -
Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization
por: Haq, Tamanna, et al.
Publicado: (2015) -
Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K
por: Ren, Gui, et al.
Publicado: (2012) -
NEK4 kinase regulates EMT to promote lung cancer metastasis
por: Ding, Nian‐Hua, et al.
Publicado: (2018)