Cargando…

Targeting Wnt/β-catenin-mediated upregulation of oncogenic NLGN3 suppresses cancer stem cells in glioblastoma

Glioblastoma (GBM) is the most malignant tumor in brain and is highly resistant to therapy. Clinical evidence suggests increased number of cancer stem cells (CSCs) may contribute to the failure of conventional therapies, but the mechanisms associated with acquisition of CSC properties in GBM are not...

Descripción completa

Detalles Bibliográficos
Autores principales: Yun, Eun-Jin, Kim, Donghwi, Kim, Sangwoo, Hsieh, Jer-Tsong, Baek, Seung Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344874/
https://www.ncbi.nlm.nih.gov/pubmed/37443071
http://dx.doi.org/10.1038/s41419-023-05967-x