MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice

Mammalian Müller glia (MG) possess limited regenerative capacities. However, the intrinsic capacity of mammalian MG to transdifferentiate to generate mature neurons without transgenic manipulations remains speculative. Here we show that MAP4K4, MAP4K6 and MAP4K7, which are conserved Misshapen subfam...

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Detalles Bibliográficos
Autores principales: Zhang, Houjian, Guo, Yuli, Yang, Yaqiong, Wang, Yuqian, Zhang, Youwen, Zhuang, Jingbin, Zhang, Yuting, Shen, Mei, Zhao, Jiankai, Zhang, Rongrong, Qiu, Yan, Li, Shiying, Hu, Jiaoyue, Li, Wei, Wu, Jianfeng, Xu, Haiwei, Fliesler, Steven J., Liao, Yi, Liu, Zuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344969/
https://www.ncbi.nlm.nih.gov/pubmed/37443319
http://dx.doi.org/10.1038/s41536-023-00310-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344969/
https://www.ncbi.nlm.nih.gov/pubmed/37443319
http://dx.doi.org/10.1038/s41536-023-00310-6

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