Hidden modes of DNA binding by human nuclear receptors

Human nuclear receptors (NRs) are a superfamily of ligand-responsive transcription factors that have central roles in cellular function. Their malfunction is linked to numerous diseases, and the ability to modulate their activity with synthetic ligands has yielded 16% of all FDA-approved drugs. NRs...

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Detalles Bibliográficos
Autores principales: Bhimsaria, Devesh, Rodríguez-Martínez, José A., Mendez-Johnson, Jacqui L., Ghoshdastidar, Debostuti, Varadarajan, Ashwin, Bansal, Manju, Daniels, Danette L., Ramanathan, Parameswaran, Ansari, Aseem Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345098/
https://www.ncbi.nlm.nih.gov/pubmed/37443151
http://dx.doi.org/10.1038/s41467-023-39577-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345098/
https://www.ncbi.nlm.nih.gov/pubmed/37443151
http://dx.doi.org/10.1038/s41467-023-39577-0

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