WFDC3 inhibits tumor metastasis by promoting the ERβ-mediated transcriptional repression of TGFBR1 in colorectal cancer

Estrogen plays a protective role in colorectal cancer (CRC) and primarily functions through estrogen receptor β (ERβ). However, clinical strategies for CRC therapy associated with ERβ are still under investigation. Our discoveries identified WFDC3 as a tumor suppressor that facilitates estrogen-indu...

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Detalles Bibliográficos
Autores principales: Liu, Tianqi, Zhao, Min, Peng, Lin, Chen, Jiangbo, Xing, Pu, Gao, Pin, Chen, Lei, Qiao, Xiaowen, Wang, Zaozao, Di, Jiabo, Qu, Hong, Jiang, Beihai, Su, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345115/
https://www.ncbi.nlm.nih.gov/pubmed/37443102
http://dx.doi.org/10.1038/s41419-023-05956-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345115/
https://www.ncbi.nlm.nih.gov/pubmed/37443102
http://dx.doi.org/10.1038/s41419-023-05956-0

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