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Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway

Obesity increases the risk for cardiovascular diseases and induces cardiomyopathy. Chronic inflammation plays a significant role in obesity-induced cardiomyopathy and may provide new therapeutic targets for this disease. Doublecortin-like kinase 1 (DCLK1) is an important target for cancer therapy an...

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Detalles Bibliográficos
Autores principales: Yang, Bin, Zhao, Yunjie, Luo, Wu, Zhu, Weiwei, Jin, Leiming, Wang, Minxiu, Ye, Lin, Wang, Yi, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345119/
https://www.ncbi.nlm.nih.gov/pubmed/37443105
http://dx.doi.org/10.1038/s41419-023-05960-4