TET1 facilitates specification of early human lineages including germ cells

Ten Eleven Translocation 1 (TET1) is a regulator of localized DNA demethylation through the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). To examine DNA demethylation in human primordial germ cell-like cells (hPGCLCs) induced from human embryonic stem cells (hESCs), we perf...

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Detalles Bibliográficos
Autores principales: Hsu, Fei-Man, Wu, Qiu Ya, Fabyanic, Emily B., Wei, Alex, Wu, Hao, Clark, Amander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345126/
https://www.ncbi.nlm.nih.gov/pubmed/37456839
http://dx.doi.org/10.1016/j.isci.2023.107191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345126/
https://www.ncbi.nlm.nih.gov/pubmed/37456839
http://dx.doi.org/10.1016/j.isci.2023.107191

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