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TET1 facilitates specification of early human lineages including germ cells
Ten Eleven Translocation 1 (TET1) is a regulator of localized DNA demethylation through the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). To examine DNA demethylation in human primordial germ cell-like cells (hPGCLCs) induced from human embryonic stem cells (hESCs), we perf...
Autores principales: | Hsu, Fei-Man, Wu, Qiu Ya, Fabyanic, Emily B., Wei, Alex, Wu, Hao, Clark, Amander T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345126/ https://www.ncbi.nlm.nih.gov/pubmed/37456839 http://dx.doi.org/10.1016/j.isci.2023.107191 |
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