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Growth factors and mechano-regulated reciprocal crosstalk with extracellular matrix tune the keratocyte–fibroblast/myofibroblast transition

Improper healing of the cornea after injury, infections or surgery can lead to corneal scar formation, which is associated with the transition of resident corneal keratocytes into activated fibroblasts and myofibroblasts (K–F/M). Myofibroblasts can create an extracellular matrix (ECM) niche in which...

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Detalles Bibliográficos
Autores principales: Pot, Simon A., Lin, Zhe, Shiu, Jauye, Benn, Mario C., Vogel, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345140/
https://www.ncbi.nlm.nih.gov/pubmed/37443325
http://dx.doi.org/10.1038/s41598-023-37776-9