Functional decomposition of metabolism allows a system-level quantification of fluxes and protein allocation towards specific metabolic functions

Quantifying the contribution of individual molecular components to complex cellular processes is a grand challenge in systems biology. Here we establish a general theoretical framework (Functional Decomposition of Metabolism, FDM) to quantify the contribution of every metabolic reaction to metabolic...

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Detalles Bibliográficos
Autores principales: Mori, Matteo, Cheng, Chuankai, Taylor, Brian R., Okano, Hiroyuki, Hwa, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345195/
https://www.ncbi.nlm.nih.gov/pubmed/37443156
http://dx.doi.org/10.1038/s41467-023-39724-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345195/
https://www.ncbi.nlm.nih.gov/pubmed/37443156
http://dx.doi.org/10.1038/s41467-023-39724-7

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