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Discovering functionally important sites in proteins

Proteins play important roles in biology, biotechnology and pharmacology, and missense variants are a common cause of disease. Discovering functionally important sites in proteins is a central but difficult problem because of the lack of large, systematic data sets. Sequence conservation can highlig...

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Detalles Bibliográficos
Autores principales: Cagiada, Matteo, Bottaro, Sandro, Lindemose, Søren, Schenstrøm, Signe M., Stein, Amelie, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345196/
https://www.ncbi.nlm.nih.gov/pubmed/37443362
http://dx.doi.org/10.1038/s41467-023-39909-0