The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper

Despite the long history of use and the knowledge of the genetics and biochemistry of E. coli, problems are still possible in obtaining a soluble form of recombinant proteins in this system. Although, soluble protein can be obtained both in the cytoplasm and in the periplasm of the bacterial cell. T...

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Detalles Bibliográficos
Autores principales: Belenkaya, Svetlana V., Merkuleva, Iuliia A., Yarovaya, Olga I., Chirkova, Varvara Yu., Sharlaeva, Elena A., Shanshin, Daniil V., Volosnikova, Ekaterina A., Vatsadze, Sergey Z., Khvostov, Mikhail V., Salakhutdinov, Nariman F., Shcherbakov, Dmitriy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345205/
https://www.ncbi.nlm.nih.gov/pubmed/37456729
http://dx.doi.org/10.3389/fbioe.2023.1187761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345205/
https://www.ncbi.nlm.nih.gov/pubmed/37456729
http://dx.doi.org/10.3389/fbioe.2023.1187761

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