Lsd1 safeguards T-cell development via suppressing endogenous retroelements and interferon responses

The histone demethylase Lsd1 has been shown to play multiple essential roles in mammalian biology. However, its physiological functions in thymocyte development remain elusive. We observed that the specific deletion of Lsd1 in thymocytes caused significant thymic atrophy and reduced peripheral T cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Miaoran, Wang, Bingbing, Sun, Wujianan, Ji, Dengyu, Zhou, Hang, Huang, Xuefeng, Yu, Minghang, Su, Ziyang, Chen, Ping, Qu, Kun, Wang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345215/
https://www.ncbi.nlm.nih.gov/pubmed/37429639
http://dx.doi.org/10.26508/lsa.202302042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345215/
https://www.ncbi.nlm.nih.gov/pubmed/37429639
http://dx.doi.org/10.26508/lsa.202302042

Ejemplares similares