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Lsd1 safeguards T-cell development via suppressing endogenous retroelements and interferon responses
The histone demethylase Lsd1 has been shown to play multiple essential roles in mammalian biology. However, its physiological functions in thymocyte development remain elusive. We observed that the specific deletion of Lsd1 in thymocytes caused significant thymic atrophy and reduced peripheral T cel...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345215/ https://www.ncbi.nlm.nih.gov/pubmed/37429639 http://dx.doi.org/10.26508/lsa.202302042 |