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PPM1H is down-regulated by ATF6 and dephosphorylates p-RPS6KB1 to inhibit progression of hepatocellular carcinoma

We have shown previously that polymorphism of activating transcription factor 6 (ATF6) is associated with susceptibility to hepatocellular carcinoma (HCC). Therefore, genes down-regulated by ATF6 might play a tumor-suppressing role. In the present study, we identified that expression of protein phos...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoshuang, Guo, Jianting, Li, Wei, Li, Chunrui, Zhu, Xilin, Liu, Ying, Wu, Xiaopan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345229/
https://www.ncbi.nlm.nih.gov/pubmed/37456776
http://dx.doi.org/10.1016/j.omtn.2023.06.013