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Linear energy transfer-inclusive models of brainstem necrosis following proton therapy of paediatric ependymoma
BACKGROUND AND PURPOSE: Radiation-induced brainstem necrosis after proton therapy is a severe toxicity with potential association to uncertainties in the proton relative biological effectiveness (RBE). A constant RBE of 1.1 is assumed clinically, but the RBE is known to vary with linear energy trans...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345333/ https://www.ncbi.nlm.nih.gov/pubmed/37457667 http://dx.doi.org/10.1016/j.phro.2023.100466 |