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Linear energy transfer-inclusive models of brainstem necrosis following proton therapy of paediatric ependymoma

BACKGROUND AND PURPOSE: Radiation-induced brainstem necrosis after proton therapy is a severe toxicity with potential association to uncertainties in the proton relative biological effectiveness (RBE). A constant RBE of 1.1 is assumed clinically, but the RBE is known to vary with linear energy trans...

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Detalles Bibliográficos
Autores principales: Handeland, Andreas H., Indelicato, Daniel J., Fredrik Fjæra, Lars, Ytre-Hauge, Kristian S., Pettersen, Helge Egil S., Muren, Ludvig P., Lassen-Ramshad, Yasmin, Stokkevåg, Camilla H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345333/
https://www.ncbi.nlm.nih.gov/pubmed/37457667
http://dx.doi.org/10.1016/j.phro.2023.100466