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Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities

Ambelline, an alkaloid from the Amaryllidaceae family with a crinane-type skeleton, has not yet demonstrated any outstanding biological activity. However, its analogues prepared by derivatization of the C-11 hydroxyl group show different interesting effects. Continuing our earlier work, twelve novel...

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Detalles Bibliográficos
Autores principales: Ritomská, Aneta, Koutova, Darja, Křoustková, Jana, Královec, Karel, Muthná, Darina, Kuneš, Jiří, Nováková, Lucie, Havelek, Radim, Cahlíková, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345363/
https://www.ncbi.nlm.nih.gov/pubmed/37457365
http://dx.doi.org/10.1016/j.jsps.2023.06.017