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Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities
Ambelline, an alkaloid from the Amaryllidaceae family with a crinane-type skeleton, has not yet demonstrated any outstanding biological activity. However, its analogues prepared by derivatization of the C-11 hydroxyl group show different interesting effects. Continuing our earlier work, twelve novel...
Autores principales: | Ritomská, Aneta, Koutova, Darja, Křoustková, Jana, Královec, Karel, Muthná, Darina, Kuneš, Jiří, Nováková, Lucie, Havelek, Radim, Cahlíková, Lucie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345363/ https://www.ncbi.nlm.nih.gov/pubmed/37457365 http://dx.doi.org/10.1016/j.jsps.2023.06.017 |
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