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Chimeric antigen receptor T-cell therapy for adult B-cell acute lymphoblastic leukemia: state-of-the-(C)ART and the road ahead

Autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy has recently been added to the armamentarium in the battle against B-cell acute lymphoblastic leukemia (B-ALL). In this review, we discuss the trials that led to US Food and Drug Administration approval of CAR T-cell therapies in pa...

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Detalles Bibliográficos
Autores principales: Pasvolsky, Oren, Kebriaei, Partow, Shah, Bijal D., Jabbour, Elias, Jain, Nitin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345854/
https://www.ncbi.nlm.nih.gov/pubmed/36912764
http://dx.doi.org/10.1182/bloodadvances.2022009462