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Formulation and In-Vitro/Ex-Vivo Characterization of Pregelled Hybrid Alginate–Chitosan Microparticles for Ocular Delivery of Ketorolac Tromethamine

Innovative hybrid chitosan–sodium alginate (Ch–Ag) microparticles (MPs) were fabricated using both the ionic gelation method as well as the pre-gelation technique. The hybrid Ch–Ag MPs were studied for size, zeta potential, morphology, mucoadhesion, in-vitro release, corneal permeation, and ocular i...

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Detalles Bibliográficos
Autores principales: Fathalla, Zeinab, Fatease, Adel Al, Abdelkader, Hamdy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346322/
https://www.ncbi.nlm.nih.gov/pubmed/37447419
http://dx.doi.org/10.3390/polym15132773