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Mesenchymal Stem Cell-Extracellular Vesicle Therapy for Stroke: Scalable Production and Imaging Biomarker Studies

A major clinical hurdle to translate MSC-derived extracellular vesicles (EVs) is the lack of a method to scale-up the production of EVs with customized therapeutic properties. In this study, we tested whether EV production by a scalable 3D-bioprocessing method is feasible and improves neuroplasticit...

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Detalles Bibliográficos
Autores principales: Son, Jeong Pyo, Kim, Eun Hee, Shin, Eun Kyoung, Kim, Dong Hee, Sung, Ji Hee, Oh, Mi Jeong, Cha, Jae Min, Chopp, Michael, Bang, Oh Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346399/
https://www.ncbi.nlm.nih.gov/pubmed/37311045
http://dx.doi.org/10.1093/stcltm/szad034