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3D micropattern force triggers YAP nuclear entry by transport across nuclear pores and modulates stem cells paracrine

Biophysical cues of the cellular microenvironment tremendously influence cell behavior by mechanotransduction. However, it is still unclear how cells sense and transduce the mechanical signals from 3D geometry to regulate cell function. Here, the mechanotransduction of human mesenchymal stem cells (...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhong, Zhenyu, Xu, Cunjing, Wu, Xiaodan, Li, Jiaqi, Tao, Weiyong, Wang, Jianglin, Du, Yingying, Zhang, Shengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347367/
https://www.ncbi.nlm.nih.gov/pubmed/37457331
http://dx.doi.org/10.1093/nsr/nwad165