Cargando…

Inhibition of P2X4 and P2X7 receptors improves histological and behavioral outcomes after experimental traumatic brain injury in rats

Release of large amounts of adenosine triphosphate (ATP), a gliotransmitter, into the extracellular space by traumatic brain injury (TBI) is considered to activate the microglia followed by release of inflammatory cytokines resulting in excessive inflammatory response that induces secondary brain in...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, Masato, Moro, Nobuhiro, Yoshino, Atsuo, Kumagawa, Takahiro, Shijo, Katsunori, Maeda, Takeshi, Oshima, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347371/
https://www.ncbi.nlm.nih.gov/pubmed/37456165
http://dx.doi.org/10.3892/etm.2023.12077