PARP2 downregulation in T cells ameliorates lipopolysaccharide-induced inflammation of the large intestine

INTRODUCTION: T cell-dependent inflammatory response with the upregulation of helper 17 T cells (Th17) and the downregulation of regulatory T cells (Treg) accompanied by the increased production of tumor necrosis alpha (TNFa) is characteristic of inflammatory bowel diseases (IBD). Modulation of T ce...

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Detalles Bibliográficos
Autores principales: Bencsics, Máté, Bányai, Bálint, Ke, Haoran, Csépányi-Kömi, Roland, Sasvári, Péter, Dantzer, Françoise, Hanini, Najat, Benkő, Rita, Horváth, Eszter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347374/
https://www.ncbi.nlm.nih.gov/pubmed/37457706
http://dx.doi.org/10.3389/fimmu.2023.1135410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347374/
https://www.ncbi.nlm.nih.gov/pubmed/37457706
http://dx.doi.org/10.3389/fimmu.2023.1135410

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