Improved single-cell genome amplification by a high-efficiency phi29 DNA polymerase

Single-cell genomic whole genome amplification (WGA) is a crucial step in single-cell sequencing, yet its low amplification efficiency, incomplete and uneven genome amplification still hinder the throughput and efficiency of single-cell sequencing workflows. Here we introduce a process called Improv...

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Detalles Bibliográficos
Autores principales: Zhang, Jia, Su, Xiaolu, Wang, Yefei, Wang, Xiaohang, Zhou, Shiqi, Jia, Hui, Jing, Xiaoyan, Gong, Yanhai, Wang, Jichao, Xu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347390/
https://www.ncbi.nlm.nih.gov/pubmed/37456715
http://dx.doi.org/10.3389/fbioe.2023.1233856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347390/
https://www.ncbi.nlm.nih.gov/pubmed/37456715
http://dx.doi.org/10.3389/fbioe.2023.1233856

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