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Improved single-cell genome amplification by a high-efficiency phi29 DNA polymerase
Single-cell genomic whole genome amplification (WGA) is a crucial step in single-cell sequencing, yet its low amplification efficiency, incomplete and uneven genome amplification still hinder the throughput and efficiency of single-cell sequencing workflows. Here we introduce a process called Improv...
Autores principales: | Zhang, Jia, Su, Xiaolu, Wang, Yefei, Wang, Xiaohang, Zhou, Shiqi, Jia, Hui, Jing, Xiaoyan, Gong, Yanhai, Wang, Jichao, Xu, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347390/ https://www.ncbi.nlm.nih.gov/pubmed/37456715 http://dx.doi.org/10.3389/fbioe.2023.1233856 |
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