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Toll-like receptor 5 tunes hepatic and pancreatic stellate cells activation

OBJECTIVE: Stellate cells are responsible for liver and pancreas fibrosis and strictly correlate with tumourigenesis. Although their activation is reversible, an exacerbated signalling triggers chronic fibrosis. Toll-like receptors (TLRs) modulate stellate cells transition. TLR5 transduces the signa...

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Detalles Bibliográficos
Autores principales: Di Fazio, Pietro, Mielke, Sophia, Böhm, Isabell T, Buchholz, Malte, Matrood, Sami, Schuppan, Detlef, Wissniowski, Thaddeus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347502/
https://www.ncbi.nlm.nih.gov/pubmed/37433685
http://dx.doi.org/10.1136/bmjgast-2023-001148