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ALKBH5-mediated m(6)A demethylation fuels cutaneous wound re-epithelialization by enhancing PELI2 mRNA stability

BACKGROUND: Impaired wound re-epithelialization contributes to cutaneous barrier reconstruction dysfunction. Recently, N(6)-methyladenosine (m(6)A) RNA modification has been shown to participate in the determination of RNA fate, and its aberration triggers the pathogenesis of numerous diseases. Howb...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Zhao, Yixuan, Liu, Daiming, Gu, Shuchen, Liu, Yunhan, Khoong, Yimin, Luo, Shenying, Zhang, Zewei, Xia, Wenzheng, Wang, Meng, Liang, Hsin, Li, Minxiong, Li, Qingfeng, Zan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347733/
https://www.ncbi.nlm.nih.gov/pubmed/37452367
http://dx.doi.org/10.1186/s41232-023-00288-0