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Percutaneous transhepatic cholangial drainage or antibiotic therapy worsens response to immunotherapy in advanced cholangiocarcinoma

BACKGROUND: Bile duct obstruction is a common issue for patients with advanced cholangiocarcinoma (CCA). Percutaneous transhepatic cholangial drainage (PTCD) is often required to relieve the obstruction. However, PTCD may alter the intestinal microbiota, which can affect the efficacy of immunotherap...

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Detalles Bibliográficos
Autores principales: Huang, Qingyu, Wang, Fuhao, Zhang, Xiang, Liu, Jing, Dou, Xue, Feng, Rui, Zhu, Kunli, Jiang, Shumei, Zhang, Yun, Yue, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347737/
https://www.ncbi.nlm.nih.gov/pubmed/37442960
http://dx.doi.org/10.1186/s12885-023-11128-2