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The Z-nucleic acid sensor ZBP1 in health and disease

Nucleic acid sensing is a central process in the immune system, with far-reaching roles in antiviral defense, autoinflammation, and cancer. Z-DNA binding protein 1 (ZBP1) is a sensor for double-stranded DNA and RNA helices in the unusual left-handed Z conformation termed Z-DNA and Z-RNA. Recent rese...

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Detalles Bibliográficos
Autores principales: Maelfait, Jonathan, Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347765/
https://www.ncbi.nlm.nih.gov/pubmed/37450010
http://dx.doi.org/10.1084/jem.20221156