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The Z-nucleic acid sensor ZBP1 in health and disease
Nucleic acid sensing is a central process in the immune system, with far-reaching roles in antiviral defense, autoinflammation, and cancer. Z-DNA binding protein 1 (ZBP1) is a sensor for double-stranded DNA and RNA helices in the unusual left-handed Z conformation termed Z-DNA and Z-RNA. Recent rese...
Autores principales: | Maelfait, Jonathan, Rehwinkel, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347765/ https://www.ncbi.nlm.nih.gov/pubmed/37450010 http://dx.doi.org/10.1084/jem.20221156 |
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