Increased prime edit rates in KCNQ2 and SCN1A via single nicking all-in-one plasmids

BACKGROUND: Prime editing (PE) is the most recent gene editing technology able to introduce targeted alterations to the genome, including single base pair changes, small insertions, and deletions. Several improvements to the PE machinery have been made in the past few years, and these have been test...

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Detalles Bibliográficos
Autores principales: Dirkx, N., Weuring, Wout J., De Vriendt, E., Smal, N., van de Vondervoort, J., van ’t Slot, Ruben, Koetsier, M., Zonnekein, N., De Pooter, Tim, Weckhuysen, S., Koeleman, B. P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347817/
https://www.ncbi.nlm.nih.gov/pubmed/37443005
http://dx.doi.org/10.1186/s12915-023-01646-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347817/
https://www.ncbi.nlm.nih.gov/pubmed/37443005
http://dx.doi.org/10.1186/s12915-023-01646-7

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