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Developing and characterizing a two-layered safety switch for cell therapies

Gene edited and engineered cell-based therapies are a promising approach for treating a variety of disorders, including cancer. However, the ability of engineered cells to persist for prolonged periods along with possible toxicity raises concerns over the safety of these approaches. Although a numbe...

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Detalles Bibliográficos
Autores principales: Rossignoli, Filippo, Hoffman, Danielle, Atif, Emaan, Shah, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348026/
https://www.ncbi.nlm.nih.gov/pubmed/37439774
http://dx.doi.org/10.1080/15384047.2023.2232146