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Immunogenicity, safety and reactogenicity of heterologous (third dose) booster vaccination with a full or fractional dose of two different COVID-19 vaccines: A phase 4, single-blind, randomized controlled trial in adults

In this phase 4 study we assessed boosting with fractional doses of heterologous COVID-19 vaccines in Brazilian adults primed with two doses of CoronaVac (Sinovac/Butantan, São Paulo, Brazil) at least 4 months previously. Participants received either full-dose of ChAdOx1-S (Group 1, n = 232), a half...

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Detalles Bibliográficos
Autores principales: Costa Clemens, Sue Ann, Marchevsky, Natalie, Kelly, Sarah, Felle, Sally, Eldawi, Ahmed, Rajasingam, Rupetha, Mahmud, Rawan, Lambe, Teresa, Voysey, Merryn, Gonzalez, Isabela, Milan, Eveline Pipolo, Justino, Maria Cleonice, Bibi, Sagida, Aley, Parvinder, Clemens, Ralf, Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348030/
https://www.ncbi.nlm.nih.gov/pubmed/37438960
http://dx.doi.org/10.1080/21645515.2023.2233400