Cargando…

Empagliflozin and Renal Sodium-Hydrogen Exchange in Healthy Subjects

CONTEXT: Sodium glucose co-transporter-2 inhibitors exert clinically relevant cardiorenal protection. Among several mechanisms, inhibition of sodium-hydrogen exchanger-3 (NHE3) in proximal renal tubules has been proposed in rodents. Demonstration of this mechanism with the associated electrolyte and...

Descripción completa

Detalles Bibliográficos
Autores principales: Biancalana, Edoardo, Rossi, Chiara, Raggi, Francesco, Distaso, Mariarosaria, Tricò, Domenico, Baldi, Simona, Ferrannini, Ele, Solini, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348461/
https://www.ncbi.nlm.nih.gov/pubmed/36794422
http://dx.doi.org/10.1210/clinem/dgad088