The synergistic effect of residues 32T and 550L in the PA protein of H5 subtype avian influenza virus contributes to viral pathogenicity in mice

The avian influenza virus (AIV) PA protein contributes to viral replication and pathogenicity; however, its interaction with innate immunity is not well understood. Here, we report that the H5 subtype AIV PA protein strongly suppresses host antiviral defense by interacting with and degrading a key p...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Dong, Yurui, Bian, Ying, Huo, Chenzhi, Zhu, Chuncheng, Qin, Tao, Chen, Sujuan, Peng, Daxin, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348578/
https://www.ncbi.nlm.nih.gov/pubmed/37399196
http://dx.doi.org/10.1371/journal.ppat.1011489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348578/
https://www.ncbi.nlm.nih.gov/pubmed/37399196
http://dx.doi.org/10.1371/journal.ppat.1011489

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