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PGE2-EP2/EP4 signaling elicits mesoCAR T cell immunosuppression in pancreatic cancer

INTRODUCTION: For many years, surgery, adjuvant and combination chemotherapy have been the cornerstone of pancreatic cancer treatment. Although these approaches have improved patient survival, relapse remains a common occurrence, necessitating the exploration of novel therapeutic strategies. CAR T c...

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Detalles Bibliográficos
Autores principales: Akbari, Behnia, Soltantoyeh, Tahereh, Shahosseini, Zahra, Jadidi-Niaragh, Farhad, Hadjati, Jamshid, Brown, Christine E., Mirzaei, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348647/
https://www.ncbi.nlm.nih.gov/pubmed/37457723
http://dx.doi.org/10.3389/fimmu.2023.1209572