Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation

Cytokinetic abscission, the last step of cell division, is regulated by the ESCRT machinery. In response to mitotic errors, ESCRT proteins, namely, ALIX, CHMP4B, and CHMP4C, accumulate in the cytosolic compartments termed “abscission checkpoint bodies” (ACBs) to delay abscission and prevent tumorige...

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Detalles Bibliográficos
Autores principales: Elias, Ruben D., Zhu, Yingqi, Su, Qi, Ghirlando, Rodolfo, Zhang, Jin, Deshmukh, Lalit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348681/
https://www.ncbi.nlm.nih.gov/pubmed/37450591
http://dx.doi.org/10.1126/sciadv.adg3913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348681/
https://www.ncbi.nlm.nih.gov/pubmed/37450591
http://dx.doi.org/10.1126/sciadv.adg3913

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