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The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study

Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood. Methods: To explore the molecular profile of AD and aged platelets, we investigated platelet activatio...

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Detalles Bibliográficos
Autores principales: de Sousa, Diana M. Bessa, Poupardin, Rodolphe, Villeda, Saul A., Schroer, Adam B., Fröhlich, Thomas, Frey, Vanessa, Staffen, Wolfgang, Mrowetz, Heike, Altendorfer, Barbara, Unger, Michael S., Iglseder, Bernhard, Paulweber, Bernhard, Trinka, Eugen, Cadamuro, Janne, Drerup, Martin, Schallmoser, Katharina, Aigner, Ludwig, Kniewallner, Kathrin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348715/
https://www.ncbi.nlm.nih.gov/pubmed/37457829
http://dx.doi.org/10.3389/fmolb.2023.1196083