Kinetochore-fiber lengths are maintained locally but coordinated globally by poles in the mammalian spindle

At each cell division, nanometer-scale components self-organize to build a micron-scale spindle. In mammalian spindles, microtubule bundles called kinetochore-fibers attach to chromosomes and focus into spindle poles. Despite evidence suggesting that poles can set spindle length, their role remains...

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Detalles Bibliográficos
Autores principales: Richter, Manuela, Neahring, Lila, Tao, Jinghui, Sutanto, Renaldo, Cho, Nathan H, Dumont, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348741/
https://www.ncbi.nlm.nih.gov/pubmed/37395732
http://dx.doi.org/10.7554/eLife.85208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348741/
https://www.ncbi.nlm.nih.gov/pubmed/37395732
http://dx.doi.org/10.7554/eLife.85208

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