Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH

Cell senescence suppresses tumors by arresting cells at risk of becoming malignant. However, this process in turn can affect the microenvironment, leading to acquisition of a senescence-associated secretory phenotype (SASP) that renders senescent cells proinflammatory and results in tumor progressio...

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Detalles Bibliográficos
Autores principales: Singh, Manvendra, Kondraskhina, Aleksandra M., Hurst, Laurence D., Izsvák, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348764/
https://www.ncbi.nlm.nih.gov/pubmed/37463444
http://dx.doi.org/10.1172/JCI172278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348764/
https://www.ncbi.nlm.nih.gov/pubmed/37463444
http://dx.doi.org/10.1172/JCI172278

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