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Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH
Cell senescence suppresses tumors by arresting cells at risk of becoming malignant. However, this process in turn can affect the microenvironment, leading to acquisition of a senescence-associated secretory phenotype (SASP) that renders senescent cells proinflammatory and results in tumor progressio...
Autores principales: | Singh, Manvendra, Kondraskhina, Aleksandra M., Hurst, Laurence D., Izsvák, Zsuzsanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348764/ https://www.ncbi.nlm.nih.gov/pubmed/37463444 http://dx.doi.org/10.1172/JCI172278 |
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