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Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin

Increased levels and diversity of human endogenous retrovirus (HERV) transcription characterize most cancer types and are linked with disease outcomes. However, the underlying processes are incompletely understood. Here, we show that elevated transcription of HERVH proviruses predicted survival of l...

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Detalles Bibliográficos
Autores principales: Attig, Jan, Pape, Judith, Doglio, Laura, Kazachenka, Anastasiya, Ottina, Eleonora, Young, George R., Enfield, Katey S.S., Aramburu, Iker Valle, Ng, Kevin W., Faulkner, Nikhil, Bolland, William, Papayannopoulos, Venizelos, Swanton, Charles, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348765/
https://www.ncbi.nlm.nih.gov/pubmed/37192000
http://dx.doi.org/10.1172/JCI164397