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Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia

Glucose is the basic fuel essential for maintenance of viability and functionality of all cells. However, some neurons — namely, glucose-inhibited (GI) neurons — paradoxically increase their firing activity in low-glucose conditions and decrease that activity in high-glucose conditions. The ionic me...

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Detalles Bibliográficos
Autores principales: Tu, Longlong, Bean, Jonathan C., He, Yang, Liu, Hailan, Yu, Meng, Liu, Hesong, Zhang, Nan, Yin, Na, Han, Junying, Scarcelli, Nikolas A., Conde, Kristine M., Wang, Mengjie, Li, Yongxiang, Feng, Bing, Gao, Peiyu, Cai, Zhao-Lin, Fukuda, Makoto, Xue, Mingshan, Tong, Qingchun, Yang, Yongjie, Liao, Lan, Xu, Jianming, Wang, Chunmei, He, Yanlin, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348766/
https://www.ncbi.nlm.nih.gov/pubmed/37261917
http://dx.doi.org/10.1172/JCI163391