Antigen-presenting aged neutrophils induce CD4(+) T cells to exacerbate inflammation in sepsis

Extracellular cold-inducible RNA-binding protein (eCIRP) is a key mediator of severity and mortality in sepsis. We found that stimulation of mouse bone marrow–derived neutrophils (BMDNs) with eCIRP generated a distinct neutrophil subpopulation, characterized by cell surface markers of both antigen-p...

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Detalles Bibliográficos
Autores principales: Jin, Hui, Aziz, Monowar, Murao, Atsushi, Kobritz, Molly, Shih, Andrew J., Adelson, Robert P., Brenner, Max, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348768/
https://www.ncbi.nlm.nih.gov/pubmed/37463445
http://dx.doi.org/10.1172/JCI164585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348768/
https://www.ncbi.nlm.nih.gov/pubmed/37463445
http://dx.doi.org/10.1172/JCI164585

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