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USP13 deubiquitinates and stabilizes cyclin D1 to promote gastric cancer cell cycle progression and cell proliferation

The reversible post-translational modifications of protein ubiquitination and deubiquitination play a crucial regulatory role in cellular homeostasis. Deubiquitinases (DUBs) are responsible for the removal of ubiquitin from the protein substrates. The dysregulation of the DUBs may give rise to the o...

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Detalles Bibliográficos
Autores principales: Ma, Cunying, Wang, Dandan, Tian, Zhuangfei, Gao, Wenrong, Zang, Yichen, Qian, Lilin, Xu, Xia, Jia, Jihui, Liu, Zhifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348911/
https://www.ncbi.nlm.nih.gov/pubmed/37311811
http://dx.doi.org/10.1038/s41388-023-02739-x