The combined action of the intracellular regions regulates FGFR2 kinase activity

Receptor tyrosine kinases (RTKs) are typically activated through a precise sequence of intracellular phosphorylation events starting with a tyrosine residue on the activation loop (A-loop) of the kinase domain (KD). From this point the mono-phosphorylated enzyme is active, but subject to stringent r...

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Detalles Bibliográficos
Autores principales: Lin, Chi-Chuan, Wieteska, Lukasz, Poncet-Montange, Guillaume, Suen, Kin Man, Arold, Stefan T., Ahmed, Zamal, Ladbury, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349056/
https://www.ncbi.nlm.nih.gov/pubmed/37452126
http://dx.doi.org/10.1038/s42003-023-05112-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349056/
https://www.ncbi.nlm.nih.gov/pubmed/37452126
http://dx.doi.org/10.1038/s42003-023-05112-6

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