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Tumor-agnostic ctDNA levels by mFAST-SeqS in first-line HR-positive, HER2 negative metastatic breast cancer patients as a biomarker for survival

This prospective cohort study reports aneuploidy score by mFast-SeqS as a strong prognostic marker in MBC patients. mFAST-SeqS is an affordable and easily implementable method for the assessment of total ctDNA levels and, as such, provides an alternative prognostic tool. One mixed cohort (cohort A,...

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Detalles Bibliográficos
Autores principales: Verschoor, Noortje, de Weerd, Vanja, Van, Mai N., Kraan, Jaco, Smid, Marcel, Heijns, Joan B., Drooger, Jan C., Zuetenhorst, Johanna M., van der Padt-Pruijsten, Annemieke, Jager, Agnes, Sleijfer, Stefan, Martens, John W. M., Wilting, Saskia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349058/
https://www.ncbi.nlm.nih.gov/pubmed/37452019
http://dx.doi.org/10.1038/s41523-023-00563-w