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Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A

The ever-growing rise of antibiotic resistance among bacterial pathogens is one of the top healthcare threats today. Although combination antibiotic therapies represent a potential approach to more efficiently combat infections caused by susceptible and drug-resistant bacteria, only a few known drug...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Wei, Leimer, Nadja, Syroegin, Egor A., Dunand, Clémence, Bulman, Zackery P., Lewis, Kim, Polikanov, Yury S., Svetlov, Maxim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349075/
https://www.ncbi.nlm.nih.gov/pubmed/37452045
http://dx.doi.org/10.1038/s41467-023-39653-5