Sequence-based drug design as a concept in computational drug design

Drug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized steps. Here, we propose a sequence-to-drug concept for comput...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Lifan, Fan, Zisheng, Chang, Jie, Yang, Ruirui, Hou, Hui, Guo, Hao, Zhang, Yinghui, Yang, Tianbiao, Zhou, Chenmao, Sui, Qibang, Chen, Zhengyang, Zheng, Chen, Hao, Xinyue, Zhang, Keke, Cui, Rongrong, Zhang, Zehong, Ma, Hudson, Ding, Yiluan, Zhang, Naixia, Lu, Xiaojie, Luo, Xiaomin, Jiang, Hualiang, Zhang, Sulin, Zheng, Mingyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349078/
https://www.ncbi.nlm.nih.gov/pubmed/37452028
http://dx.doi.org/10.1038/s41467-023-39856-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349078/
https://www.ncbi.nlm.nih.gov/pubmed/37452028
http://dx.doi.org/10.1038/s41467-023-39856-w

Ejemplares similares